The 1CPN model is built using a rigorous multi-scale approach based on free energies obtained using the detailed 3SPN-AICG nucleosome model.
Interested in the impact of histone modifications on chromatin structure? or DNA sequence? or the linker histone? or detailed dynamics? The 1CPN model can capture it all.
Implemented in LAMMPS and built from the ground up for speed, the 1CPN model scales across hundreds of processors, and can easily simulate many kilobases of DNA.
Former Ph.D. @ U Chicago, currently UCSB
Former Post-Doc @ U Chicago, currently Universidad de Concepción
Graduate Student @ U Chicago
Professor @ U Chicago